Should testosterone be added to estrogen-progestin therapy for breast protection?
نویسنده
چکیده
منابع مشابه
Postmenopausal testosterone therapy and breast cancer risk.
BACKGROUND Testosterone therapy is being increasingly used in the management of postmenopausal women. However, as clinical trials have demonstrated a significantly increased risk of breast cancer with oral combined estrogen-progestin therapy, there is a need to ascertain the risk of including testosterone in such regimens. OBJECTIVE Evaluation of experimental and epidemiological studies perta...
متن کاملTestosterone effects on the breast: implications for testosterone therapy for women.
Androgens have important physiological effects in women. Postmenopausal androgen replacement, most commonly as testosterone therapy, is becoming increasingly widespread. This is despite the lack of clear guidelines regarding the diagnosis of androgen insufficiency, optimal therapeutic doses, and long-term safety data. With respect to the breast specifically, there is the potential for exogenous...
متن کاملBioTE HRT/BHRT MetaAnalysis
There have been many articles published regarding the benefits of HRT and BHRT; particularly in breast cancer, prostate cancer, cardiovascular protection, and bone building/osteoarthritis. The purpose of this white paper is to summarize the results of these articles by each disease entity. Please note, however, that most of the articles did not specify HRT or BHRT, but the hormone therapy itsel...
متن کاملCombined estrogen and testosterone use and risk of breast cancer in postmenopausal women.
BACKGROUND The role of androgens in breast cancer etiology has been unclear. Epidemiologic studies suggest that endogenous testosterone levels are positively associated with breast cancer risk in postmenopausal women. Given the increasing trend in the use of hormone therapies containing androgens, we evaluated the relation between the use of estrogen and testosterone therapies and breast cancer...
متن کاملRe: effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin.
The report by Ross et al. (1) in the February 16, 2000, issue of the Journal concludes that a combination of estrogen and progestin increases the risk of breast cancer over time when compared with estrogen alone. A similar conclusion was recently reported in a paper in the Journal of the American Medical Association by Schairer et al. (2). There is little question that hormone therapy, either e...
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عنوان ژورنال:
- Menopause
دوره 14 2 شماره
صفحات -
تاریخ انتشار 2007